RESUMO
In 830 Viennese school children of both sexes, aged 11-12 years, plasma carotene, retinol and alpha-tocopherol, erythrocyte transketolase activity (alpha ETK), erythrocyte glutathione-reductase (alpha EGR) and erythrocyte glutamic acid oxalacetic acid transaminase (alpha EGOT) were determined. The mean alpha ETK value indicated inadequate thiamine supply. The vitamin status was better in boys and in children of higher socio-economic classes than in girls and in the low income group, with respect to beta-carotene, retinol, tocopherol, thiamine and riboflavin. The opposite situation was true in the case of pyridoxine where the girls and the children of lower socio-economic status showed lower values for alpha EGOT indicating a better vitamin B6 status. Eating habits of the children did not seem to affect the vitamin status, but in children with overweight higher values for retinol and thiamine were more frequent and a positive correlation was found between tocopherol values and serum cholesterol.
Assuntos
Vitamina A/metabolismo , Complexo Vitamínico B/metabolismo , Vitamina E/metabolismo , Áustria , Criança , Feminino , Nível de Saúde , Humanos , Masculino , Inquéritos Nutricionais , Piridoxina/metabolismo , Riboflavina/metabolismo , Fatores Sexuais , Fatores Socioeconômicos , Tiamina/metabolismo , Deficiência de Tiamina/epidemiologiaRESUMO
Serum lipid values were determined in the first degree relatives of 31 children within the framework of a screening programme for cardiovascular-disease risk factors in schoolchildren of either sex (11 to 12 years old). Familial hyperlipoproteinaemia was not present in 5 families. The investigations revealed 12 families with hypercholesterolaemia and 2 with hypertriglyceridaemia. 12 families showed that form of hyperlipoproteinaemia which has been described in the literature as "familial combined" or "multiple type" hyperlipoproteinaemia. Spontaneous variation in serum lipids was observed in 4 out of the 12 above-mentioned children when determinations were repeated. The variability in expression of hyperlipoproteinaemia in the individual case, as well as in families, is one of the reasons for the controversy over the classification of hyperlipoproteinaemias. It is well known that hyperlipoproteinaemia, especially of the familial type, represents a significant risk factor for cardiovascular disease. Thus, it is essential to treat persons with elevated serum cholesterol or triglyceride values and to examine their relatives for hyperlipoproteinaemia.
Assuntos
Hiperlipidemias/epidemiologia , Hiperlipidemias/genética , Áustria , Criança , Colesterol/sangue , Feminino , Humanos , Hiperlipidemias/sangue , Hiperlipidemias/classificação , Masculino , Triglicerídeos/sangueRESUMO
1. The results obtained for 236 Viennese schoolchildren between 11 and 12 years of age indicated that 38% of children had an increased concentration of cholesterol in their serum and 3% had an increased serum triglyceride concentration. 2. The results of the preliminary study suggested that, by extending the dimensions of the screening, further problems, for example the correlation between different 'risk' factors and the significance of nutritional habits, might be studied.
